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The Case for Indie Drugs
The uncomfortable truth about our Ozempic obsession
Jul 1
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Joey DeBruin
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The Case for Indie Drugs
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The Quantum State of Startup Pivots
Reflections from the edge of success
Apr 18
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Joey DeBruin
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The Quantum State of Startup Pivots
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Leeches, Cancer Abstracts, and Coming Home
Why now is the time to pursue problems you genuinely care about. Also, we’re hiring.
Mar 10
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Joey DeBruin
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Leeches, Cancer Abstracts, and Coming Home
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AI Will Make Cold Outreach More Valuable, Not Less
The counterintuitive case for investing in outreach automation
Feb 25
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Joey DeBruin
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AI Will Make Cold Outreach More Valuable, Not Less
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Where the AI-as-Employee Model Breaks
Agents don't onboard like humans, and that's a good thing for niche industries
Feb 19
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Joey DeBruin
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Where the AI-as-Employee Model Breaks
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Will AI make science's reproducibility crisis worse?
Obviously — but is there room for optimism in the long run?
Feb 5
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Joey DeBruin
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Will AI make science's reproducibility crisis worse?
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How We’re Speedrunning Biotech Market Research with AI
A peek under the hood at the workflows we use to map a complex industry
Jan 28
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Joey DeBruin
5
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How We’re Speedrunning Biotech Market Research with AI
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Build a Stylesheet to Make AI Actually Sound Like You
A simple hack to create consistent, authentic AI content (and a free tool to generate one from any Substack)
Jan 22
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Joey DeBruin
5
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Build a Stylesheet to Make AI Actually Sound Like You
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Decoding how great products will be built in an increasingly digital world
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